Guido Marcucci,Bin Zhang,Ya-Huei Kuo,Marcin Tomasz Kortylewski
申请号:
US16810739
公开号:
US20200281982A1
申请日:
2020.03.05
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Provided herein are, inter alia, methods of treating red blood cell disorders and cancer using anti-miR126 compounds. The methods include administering phosphorothioated CpG oligodeoxynucleotides conjugated to an anti-miR126 nucleic acid sequence to treat red blood cell disorders. Other methods provided herein include administering phosphorothioated CpG oligodeoxynucleotides conjugated to an anti-miR126 nucleic acid sequence and a tyrosine kinase inhibitor to treat cancer.