RENFORCEMENT DES REPONSES IMMUNITAIRES DONT LA MEDIATION EST ASSUREE PAR UNE PROTEINE DE FUSION ANTICORP-CYTOKINE VIA LE TRAITEMENT COMBINE A BASE D'AGENTS AMELIORANT LA FIXATION DES IMMUNOCYTOKINES

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专利权人:

LEXIGEN PHARMACEUTICALS CORP.

发明人:

GILLIES, STEPHEN D.,LAN, YAN,HOLDEN, SYLVIA A.

申请号：

CA2412845

公开号：

CA2412845C

申请日:

2001.06.29

申请国别(地区):

CA

年份:

2014

代理人:

摘要：

Disclosed are compositions for treating tumors and the use of suchcompositions. Disclosed compositions enhance the uptake of immunocytokinesintotumors, and are based on a combination of an immunocytokine with animmunocytokineuptake enhancing agent. The immune uptake enhancing agent is taxol, docetaxel,10-deacetylBaccatin III, cyclophosphamid or carboplatin, and can be administered to amammal prior to the immunokine. Disclosed compositions are particularly usefulforreducing tumor size and metastasis in a mammal.

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