PURPOSE: A manufacturing method of a nutritional globulus is provided to provide necessary folic acid to expecting and nursing mothers by containing melon powder with a high content of folic acid. CONSTITUTION: A manufacturing method of a nutritional globulus comprises: a globulus manufacturing step to manufacture a mixture containing melon powder into a globulus; a fermentation step to ferment the same by mixing a globulus with honey and sticky glue; and a first manufacturing step to dry the fermented globulus after putting the same into the bamboo container and stemming. After the first manufacturing step, a second manufacturing step repeats several drying processes after steaming and mixing bean water extract with the globulus. The second manufacturing step is repeated eight times. A fermentation step comprises injecting 100 parts by weight of globulus, 1-5 parts of rice, and 1-5 parts of honey into a crock and fermenting for 10 days. A mixture contained melon powder comprises 1-5 parts by weight of yeast powder, 1-5 parts of walnut, 1-5 parts of chitosan, 1-5 parts of ginseng, 1-5 parts of fermented soybean powder, 1-5 parts of seaweed, 1-5 parts of pumpkin powder, 1-5 parts of a Chinese medicine ingredient, 1-5 parts of grain powder, and 5-15 parts of bean water extract with 20 parts by weight of melon. The Chinese medicine ingredient comprises more than one selected from a group consisting of Gastrodia, antler, white Hoelen cum Radix, and cornus fruit. Grain powder comprises more than one selected from a group consisting of black rice, black soybean, and black sesame. Bean water extract is made of mixing 100 parts by weight of Rhynchosia volubilis in boiled water with 20-50 parts by weight of pine bud extract. [Reference numerals] (AA) Start; (BB) End; (S101) Globulus manufacturing step; (S103) Fermentation step; (S105) First processing step본 발명은 엽산의 함량이 높은 참외분말이 함유된 영양환의 제조방법에 관한 것으로, 더욱 상세하게는 참외분말이 함유된 혼합물을 환으로 제조하는 환제조단계, 전술한 환제조단계에서 제조된 환에 찹쌀풀과 꿀을 혼합하여 발효시