John Dangerfield,Eva Maria Brandtner,Wee Jin Tan,Christoph Metzner
申请号：
US15909194
公开号：
US20180185472A1
申请日:
2018.03.01
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention relates to a method to modify and/or to isolate exosomes and other naturally occurring plasma membrane derived microvesicles, by incubation with a reactant, consisting of at least a membrane anchor domain or moiety and a hydrophilic functional domain or moiety. The invention also relates to modification using the same of artificially-prepared lipid bilayer vesicles called liposomes (composed of natural phospholipids) and non-biological or “synthetic” block copolymer membrane mimics which also form vesicles in aqueous solution called polymersomes.
