NEEDHAM, DAVID,CHEN, WEI,MOOK, ROBERT A., JR.,WANG, JIANGBO,REN, XIU-RONG,CHEN, MINYONG,BARAK, LAWRENCE S.,LYERLY, HERBERT KIM
申请号：
CA2986930
公开号：
CA2986930A1
申请日:
2016.06.24
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
Described are methods of treating a disease associated with dysregulation of the Wnt/Frizzled signaling pathway. The methods include identifying subjects in need of therapy, administering inhibitors of the Wnt/Frizzled signaling pathway, pharmaceutical compositions including the inhibitors, and methods of using the compounds and compositions for treating cancer, bacterial and viral infection, lupus, type II diabetes, nonalcoholic steatohepatitis (NASH) and nonalcoholic fatty liver disease (NAFLD) in a subject.
