Alnylam Pharmaceuticals, Inc.;The UAB Research Foundation
发明人:
David Erbe,Abigail Liebow,Kevin Fitzgerald,Gregory Hinkle,Kyle David Wood,Ross Philip Holmes,John Knight
申请号：
US16811476
公开号：
US20200206258A1
申请日:
2020.03.06
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The invention relates to double-stranded ribonucleic acid (dsRNA) compositions targeting the LDHA gene, as well as methods of inhibiting expression of LDHA, methods of inhibiting LDHA and HAO1, and methods of treating subjects that would benefit from reduction in expression of LDHA, such as subjects having an oxalate pathway-associated disease, disorder, or condition, using such dsRNA compositions.
