Changyu WANG,Nils LONBERG,Alan J. KORMAN,Mark J. SELBY,Mohan SRINIVASAN,Karla HENNING,Michelle Minhua HAN,Guodong CHEN,Richard HUANG,Indrani CHAKRABORTY,Haichun HUANG,Susan WONG,Huiming LI
申请号:
US16578987
公开号:
US20200079865A1
申请日:
2019.09.23
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Provided herein are antibodies, or antigen binding portions thereof, that bind to glucocorticoid-inducible TNF receptor (GITR). Also provided are uses of these proteins in therapeutic applications, such as in the treatment of cancer. Further provided are cells that produce the antibodies, polynucleotides encoding the heavy and/or light chain variable region of the antibodies, and vectors comprising the polynucleotides encoding the heavy and/or light chain variable region of the antibodies.