Ji Hyun BAE;Nok Hyun PARK;Ji Yeong KIM;Jun Cheol CHO;Yong Joo NA
发明人:
Nok Hyun PARK,Yong Joo NA,Ji Yeong KIM,Ji Hyun BAE,Jun Cheol CHO
申请号：
US13189168
公开号：
US20120022151A1
申请日:
2011.07.22
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Provided are a method for preventing damage to the nuclear membrane of skin cell including administering an effective amount of amentoflavone to a subject and a method for anti-aging including administering an effective amount of amentoflavone to a subject. By controlling the expression of defective lamin A induced by UV radiation or controlling the expression of phosphorylated H2A histone family, member X (H2AX) induced by UV radiation, the disclosed method prevents nuclear membrane damage and thus prevents skin cell damage. Accordingly, a composition containing amentoflavone as an active ingredient may be used as a cosmetic composition or a pharmaceutical composition.
