A catheter for delivering, a hyperthermic liquid to the interior of an organ of a patient includes an inflow lumen structured to be inserted into the organ and deliver the hyperthermic liquid to the interior of the organ, and an outflow lumen structured to be inserted into the organ and evacuate the hyperthermic liquid from the interior of the organ. The catheter includes a proximal portion that is structured to be received within the internal tissue structure of the patient, wherein at least a portion of the inflow lumen and the outflow lumen are insulated in a manner wherein a temperature on an outside surface of the proximal portion of the catheter will not be more than one degree Fahrenheit above normal body temperature when the hyperthermic liquid is passed through the catheter.