Ravindra Kumar,Pedro Martinez,Naga Venkata Sai Rajasekhar Suragani
申请号:
US15343757
公开号:
US20170274077A1
申请日:
2016.11.04
申请国别(地区):
US
年份:
2017
代理人:
摘要:
In certain aspects, the present disclosure provides compositions and methods for increasing red blood cell and/or hemoglobin levels in a subject in need thereof. Subjects in need include, for example, subjects having anemia and/or ineffective erythropoiesis as a result of having reduced GATA-1, heat shock factor and/or NFE2 levels as compared to the levels in a reference population.