Francois WILHELM;Manjo MANIAR;Azra RAZA;ONCONOVA THERAPEUTICS, INC.;THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
发明人:
MANOJ MANIAR,AZRA RAZA,FRANCOIS WILHELM
申请号:
US14649759
公开号:
US20150313859A1
申请日:
2013.12.06
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The invention discloses a method of treating cancer refractory to an anticancer agent comprising administering to a cancer patient a pharmaceutical composition comprising at least one compound of Formula 1Where R1 is selected from the group consisting of —NH2, —NH—CH2—COOH, —NH—CH(CH3)—COOH, —NH—C(CH3)2—COOH, —NH—CH2—CH2—OH and —N—(CH2CH2OH)2 or a pharmaceutically acceptable salt of such a compound, and an anticancer agent.