The method that this Hair Ming Department Off Yu mono- Seed give birth to element D2 derivatives (paricalcitol, Paricalcitol) by anti-phase color Layer analytic approach Pureization Victoria. This Hair Ming Ye Off whats by The Pureization method Suo System Prepare paricalcitol. The method that this Hair Ming Jin mono- Bu Off Yu mono- Seed Ji You Knot crystalline substances act on Pureization paricalcitol.本發明係關於一種藉由逆相色層分析法純化維生素D2衍生物(帕立骨化醇,Paricalcitol)的方法。本發明也關於由該純化方法所製備的帕立骨化醇。本發明進一步關於一種藉由結晶作用純化帕立骨化醇的方法。