The present invention relates to productions to have many advantages, such as in conjunction with active monoclonal antibody to many high-risk HPV s. The present invention also provides a kind of methods simply with high-throughput measurement cross-neutralization antibody titer, and the cross-neutralization antibody of HPV is in serum and object It is other. The neutralizing antibody titers measurement method of this cross reaction involves the steps of production monoclonal antibody and the peptide comprising specific amino acid sequence is to use the monoclonal antibody in high-risk HPV s measurement cross-neutralization antibody.
