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原核生物、菌類、原生動物もしくは藻類などの微生物中で、または微生物から核酸を安定化および/または単離するための、カチオン化合物およびプロトン供与体からなる組成物の使用
专利权人:
发明人:
申请号:
JP20020505350
公开号:
JP5657847(B2)
申请日:
2001.06.26
申请国别(地区):
日本
年份:
2015
代理人:
摘要:

#CMT# #/CMT# Composition (A) comprises specific cationic compound (I) and at least one proton donor (II). #CMT# : #/CMT# Composition (A) comprises specific cationic compound of formula (I) and at least one proton donor (II). Y +>R 1R 2R 3R 4 X -> (I) Y : nitrogen or phosphorus; R 1-R 4linear or branched 1-20C alkyl, 6-20C aryl or 6-26C aralkyl; and X : anion of a mono- or poly-basic (in)organic acid. Independent claims are also included for the following: (a) method for preparing (A); (b) diagnostic composition, and kit for stabilizing nucleic acid (NA), containing (A); and (c) mixture of NA-containing biological sample, (A) and optionally other auxiliaries. #CMT#USE : #/CMT# (A) is used to isolate and/or stabilize nucleic acid (NA) in biological samples, particularly for subsequent analysis, especially for diagnosis (of tumors, inherited diseases, infections by viruses or other pathogens); determination of expression patterns (in clinical samples, bacteria or plants) or for analysis of foods. #CMT#ADVANTA

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