Immunoglobulin-like molecules directed against fibronectin-eda

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专利权人:

UMC UTRECHT HOLDING B.V.

发明人:

Arslan, Fatih

申请号：

NZ72198414

公开号：

NZ721984A

申请日:

2014.12.12

申请国别(地区):

NZ

年份:

2020

代理人:

摘要：

The present invention is concerned with immunoglobulin (Ig)-like molecules or fragments thereof for use in treatment, or prevention of progression of adverse cardiac remodelling and conditions resulting from or relating to myocardial infarction and pressure-overload, such as heart failure, aneurysm formation and remote myocardial fibrosis and for use in improving angiogenesis, preferably after ischemic injury. The invention also provides nucleic acid molecules encoding said Ig-like molecules, vectors comprising same, and host cells comprising same.

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