Deodhar, Mandar,Findlay, Alison Dorothy,Foot, Jonathan Stuart,Jarolimek, Wolfgang,Mcdonald, Ian Alexander,Alan Robertson,Craig Ivan Turner
申请号:
AU2013203655
公开号:
AU2013203655A1
申请日:
2013.04.11
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
#$%^&*AU2013203655A120131121.pdf#####98 ABSTRACT The present invention is related to the preparation and pharmaceutical use of substituted 3-haloallylamine derivatives as SSAO/VAP-1 inhibitors having the structure of Formula I, as defined in the specification: R 4 R3 R2 R5 H R1 Formula I The invention also relates to methods of using compounds of Formula I, or pharmaceutically acceptable salt or derivatives thereof, for the treatment of a variety of indications, e.g., inflammatory diseases, ocular diseases, fibrotic diseases, diabetesinduced diseases and cancer.