The present invention relates to a cork for a medicine bottle. The cork for a medicine bottle is used for medical purposes and comprises: a body made of a chlorobutyl material and a coating layer formed by using fluorine with the regular thickness on one side of the body. According to the present invention, the coating layer of a fluorine material is formed on the surface of chlorobutyl rubber so a coating process is simplified and process costs are significantly reduced. Also, performance of the coating layer can be significantly improved.COPYRIGHT KIPO 2017본 발명은 약병용 마개에 관한 것으로 그 구성은 의료용에 이용되는 약병용 마개에 있어서, 클로로 부칠 소재로 형성된 몸체 및 상기 몸체 일측에 일정한 두께의 불소를 이용해 형성된 코팅층을 포함한다.