There is provided a tryptophan-2,3-dioxygenase (TDO) and / or indoleamine-2,3-dioxygenase (IDO) inhibitor compound for use in medicine, said compound having the formula (I) Medium, X1And X2Are the same or different and are independently selected from C, N, O and S； X3, X4, X5And X6Are the same or different and independently selected from C and N； each bond represented by a dotted line is present or absent, provided that at least one bond is present； R1, R2, R3, R4, R5And R6Are present or absent and are the same or different and are independently selected from H and substituted or unsubstituted organic groups and the existing R1, R2, R3, R4, R5And R6The number of groups is X1, X2, X3, X4, X5And X6Individual valences of R are maintained； R5And R6At least one of which contains a group Y and Y is a group having a formula selected from (II), (III), (IV), (V), (VI), (VII) Which may be a substituted or unsubstituted organic linking group； R31And R32Are the same or different and are selected from H and a substituted or unsubstituted organic group； each R34Are the same or different and are selected from H and substituted or unsubstituted organic groups； R35Is selected from substituted or unsubstituted alcohol groups or ether groups； each R36Are the same or different and are selected from H and substituted or unsubstituted organic groups； X7Is selected from C and N； X8, X9, X10, X11, X12, X13, X14, X15And X16Are the same or different and independently selected from C, N, O and S； each bond represented by a dotted line is present or absent； each R313Are the same or different and are selected from H and substituted or unsubstituted organic groups. Embedded image医療で使用されるトリプトファン－２，３－ジオキシゲナーゼ（ＴＤＯ）及び／又はインドールアミン－２，３－ジオキシゲナーゼ（ＩＤＯ）阻害剤化合物が提供され、該化合物は式（Ｉ）を有し、式中、Ｘ１及びＸ２は同一又は異なって、独立にＣ、Ｎ、Ｏ及びＳから選択され；Ｘ３、Ｘ４、Ｘ５及びＸ６は同一又は異なって、独立にＣ及びＮから選択され；点線で表される各結合は、存在又は非存在であり、但し少なくとも一の結合が存在し；Ｒ１、Ｒ２、Ｒ３、Ｒ４、Ｒ５及びＲ６は、存在又は非存在であり、同一又は異なって、独立にＨ及び置換又は未置換の有機基から選択され、存在するＲ１、Ｒ２、Ｒ３、Ｒ４、Ｒ５及びＲ６基の数は、Ｘ１、Ｘ２、Ｘ３、Ｘ４、Ｘ５及びＸ６の個々の価数が維持
