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COMPOSÉ POUR LA PRÉVENTION OU LE TRAITEMENT DE LA MYASTHÉNIE GRAVE
专利权人:
Ablevia biotech GmbH
发明人:
申请号:
EP19164786.6
公开号:
EP3715376A1
申请日:
2019.03.23
申请国别(地区):
EP
年份:
2020
代理人:
摘要:
The present invention provides a compound for the sequestration of anti human muscle nicotinic acetylcholine receptor (AChR) antibodies present in a human individual, the compound comprising a biopolymer scaffold and at least two peptides with a sequence length of 7-13 amino acids, wherein each of the peptides independently comprises a 7-13 amino-acid sequence fragment of the AChR subunit alpha sequence identified by UniProt accession code P02708, wherein the peptides are covalently bound to the biopolymer scaffold, wherein the biopolymer scaffold is selected from the group consisting of human globulins and human albumin. This compound is useful in the prevention or treatment of myasthenia gravis.
来源网站:
中国工程科技知识中心
来源网址:
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