The present invention relates to a pharmaceutical composition for combination therapy for preventing and/or treating cancer comprising a c-Met inhibitor and a beta-catenin inhibitor as active ingredients, to use of c-Met inhibitor efficacy enhancement by the beta-catenin inhibitor, and use of beta-catenin inhibitor efficacy enhancement by the c-Met inhibitor. The combination therapy of the c-Met inhibitor and beta-catenin inhibitor enables treatment of diseases which could not be treated by the c-Met inhibitor alone, thereby extending indications and overcoming resistance against the c-Met inhibitor.COPYRIGHT KIPO 2015c-Met 저해제 및 베타-카테닌 저해제를 유효성분으로 포함하는 암의 예방 및/또는 치료를 위한 병용 투여용 약학 조성물, 베타-카테닌 저해제의 c-Met 저해제 효능 증진 용도, 및 c-Met 저해제의 베타-카테닌 저해제 효능 증진 용도가 제공된다.