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3- and 6-quinolines with N-attached heterocyclic CGRP receptor antagonists
专利权人:
Michael R. Wood
发明人:
Michael R. Wood,Ian M. Bell,June J. Kim,Harold G. Selnick,Craig A. Stump
申请号:
US13059164
公开号:
US08507477B2
申请日:
2009.08.14
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Compounds of Formula (I): (where variables R1A, R1B, R2, R3, R4, A, and Z are as defined herein) which are useful as antagonists of CGRP receptors, and useful in the treatment or prevention of diseases in which CGRP receptors are involved, such as headache, and in particular migraine and cluster headache. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP receptors are involved.
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