Antonio NARDI,Klaus SCHIENE,Thomas CHRISTOPH,Sebastian WACHTEN,Irmgard BÖSL,Andreas SCHOLZ,Ingo FRIEDRICH,Sebastian ULLRICH,Simone KÖNIG
申请号：
US16481613
公开号：
US20190374481A1
申请日:
2018.01.29
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The invention relates to a pharmaceutical patch comprising a Lidocaine constituent and a Diclofenac constituent, wherein the relative weight content ratio of the Lidocaine constituent to the Diclofenac constituent is within the range of from about 7:1 to about 4:1, based on the equivalent weight of the non-salt form of Lidocaine and of Diclofenac, for use in the local treatment or prevention of pain. The pharmaceutical composition is suitable for topical administration and local pharmacological action via delivery of Lidocaine and Diclofenac into the skin and possibly also through and to other deeper tissues such as the synovial fluid without significant systemic exposure.
