PROBLEM TO BE SOLVED: To provide a means for detecting the pain of a patient during a surgery and treatment under sedation, thereby evaluating the painkilling degree of a painkiller administered for the surgery and the treatment and managing the painkilling of the patient during the surgery and the treatment.SOLUTION: There are provided a method of detecting the pain of the patient in endoscopic submucosal dissection under conscious sedation, in which amylase in a salivary specimen or its activity is an objective index, the method of evaluating the painkilling degree by the painkiller during the surgery, the painkilling management method during the surgery, a medicine supplying device and a reporting device for painkilling management.COPYRIGHT: (C)2010,JPO&INPIT【課題】鎮静下における手術および処置中の患者の痛みを検出し、それにより手術および処置の為に投与された鎮痛剤の鎮痛度を評価し、また、手術および処置中の患者の鎮痛管理を行う手段を提供する。【解決手段】唾液試料中のアミラーゼまたはその活性を客観的指標とする、意識下鎮静法下の内視鏡的粘膜下層剥離術における患者の痛みの検出方法、該術中の鎮痛剤による鎮痛度の評価方法、および該術中の鎮痛管理方法、並びに鎮痛管理用の薬剤供給装置および報知装置を提供する。【選択図】図1
