カルボン酸含有生体組織接着剤及びその調製方法
- 专利权人:
- 一般財団法人化学及血清療法研究所
- 发明人:
- 嵯峨 秀樹,荒木 辰也,羽室 強,川村 亮一,副島 見事,嘉悦 洋,平嶋 正樹,今村 隆幸
- 申请号:
- JP2008230369
- 公开号:
- JP5292025B2
- 申请日:
- 2008.09.09
- 申请国别(地区):
- JP
- 年份:
- 2013
- 代理人:
- 摘要:
PROBLEM TO BE SOLVED: To provide a carboxylic acid-containing biomedical tissue adhesive and a method of preparing the same.
SOLUTION: A biomedical tissue adhesive consists of fibrinogen composition containing carboxylic acid or salt thereof at a rate of 0.05 mmol or more with respect to 40 mg of fibrinogen and a thrombin composition, a biomedical tissue adhesive is formed by applying at least one of the fibrinogen composition or the thrombin composition to a bioabsorbable sheet, and methods of preparing these biomedical tissue adhesives. The carboxylic acid or salt thereof is used by combining one or a plurality of acids selected from a group consisting of acetic acid, glutamic acid, citric acid, tartaric acid, aspartic acid, malic acid, succinic acid and salts thereof.
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- 来源网站:
- 中国工程科技知识中心