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カルボン酸含有生体組織接着剤及びその調製方法
专利权人:
一般財団法人化学及血清療法研究所
发明人:
嵯峨 秀樹,荒木 辰也,羽室 強,川村 亮一,副島 見事,嘉悦 洋,平嶋 正樹,今村 隆幸
申请号:
JP2008230369
公开号:
JP5292025B2
申请日:
2008.09.09
申请国别(地区):
JP
年份:
2013
代理人:
摘要:

PROBLEM TO BE SOLVED: To provide a carboxylic acid-containing biomedical tissue adhesive and a method of preparing the same.

SOLUTION: A biomedical tissue adhesive consists of fibrinogen composition containing carboxylic acid or salt thereof at a rate of 0.05 mmol or more with respect to 40 mg of fibrinogen and a thrombin composition, a biomedical tissue adhesive is formed by applying at least one of the fibrinogen composition or the thrombin composition to a bioabsorbable sheet, and methods of preparing these biomedical tissue adhesives. The carboxylic acid or salt thereof is used by combining one or a plurality of acids selected from a group consisting of acetic acid, glutamic acid, citric acid, tartaric acid, aspartic acid, malic acid, succinic acid and salts thereof.

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