YU, YI,CAI, ZHIJUN,WOMACK, JAMES,EARNSHAW, ANDREW MARK
申请号:
HK12106016.3
公开号:
HK1165630B
申请日:
2011.04.27
申请国别(地区):
HK
年份:
2014
代理人:
摘要:
Described herein are compositions and methods for treating a subject suffering from a non-localized inflammatory condition (or any symptoms associated with such inflammation), including systemic inflammation, and inflammatory conditions affecting the large portions of or the whole body, or sepsis by administering to the subject a pharmaceutical composition comprising a therapeutically effective amount of a compound that is a pan-HDAC inhibitor. Also described herein are methods for decreasing iNOS and cytokine expression by administering to the subject a pharmaceutical composition comprising a therapeutically effective amount of a compound that is a pan-HDAC inhibitor.