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用於治療癌症和病毒感染的免疫受體調節
专利权人:
The Council of the Queensland Institute of Medical Research
发明人:
SMYTBE, Mark
申请号:
HK16113673.9
公开号:
HK1225396A
申请日:
2016.12.01
申请国别(地区):
HK
年份:
2017
代理人:
摘要:
A method of reducing or relieving immune inhibition in a mammal includes the step of at least partly inhibiting or reducing CD96 activity in one or more cells of the mammal to thereby relieve immune inhibition and/or enhance or restore immune surveillance in the mammal. Typically, inhibiting or reducing CD96 activity does not include, or depend upon, killing of CD96-expressing cells in the mammal. The method relieves immune inhibition and/or enhances or restores immune surveillance in the mammal to thereby treat or prevent cancer or cancer metastasis and/or a viral infection in the mammal. Also provided is a method of screening, designing, engineering or otherwise producing a CD96-inhibitory agent that relieves immune inhibition and/or enhances or restores immune surveillance in a mammal. Typically, the CD96-inhibitory agent is an antibody or antibody fragment.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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