PURCELL NGAMBO, LISA,MUJICA, ALEXANDER O.,TANG, YAJUN
申请号:
CA3014645
公开号:
CA3014645A1
申请日:
2017.02.27
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
Genetically modified rodents such as mice and rats, and methods and compositions for making and using the same, are provided. The rodents comprise a humanization of at least one endogenous rodent Tmprss gene, such as an endogenous rodent Tmprss2, Tmprss4, or Tmprss11d gene.