ANTIBODY-drug conjugate

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专利权人:

DAIICHI SANKYO COMPANY; LIMITED

发明人:

MASUDA, Takeshi,NAITO, Hiroyuki,YOSHIDA, Masao,ASHIDA, Shinji,MIYAZAKI, Hideki,KASUYA, Yuji,MORITA, Koji,ABE, Yuki,OGITANI, Yusuke,NAKADA, Takashi

申请号：

DK13845596

公开号：

DK2907824T3

申请日:

2013.10.10

申请国别(地区):

DK

年份:

2018

代理人:

摘要：

As an antitumor drug which is excellent in terms of antitumor effect and safety, there is provided an antibody-drug conjugate in which an antitumor compound represented by the following formula is conjugated to an antibody via a linker having a structure represented by the following formula: -L 1 -L 2 -L P -NH-(CH 2 )n 1 -L a -L b -L c -wherein the antibody is connected to the terminal of L 1 , and the antitumor compound is connected to the terminal of L c with the nitrogen atom of the amino group at position 1 as a connecting position.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/