Sei Kwang HAHN,Kitae Park,Jeonga Yang,Won Ho Kong,Min Young Lee
申请号：
US15151632
公开号：
US20160243246A1
申请日:
2016.05.11
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The present invention relates to a hyaluronic acid-nucleic acid conjugate for the development of in vivo nucleic acid delivery system, and the development of nucleic acid delivery system using the same. Specifically, a hyaluronic acid-nucleic acid complex wherein a hyaluronic acid-alkylenediamine conjugate and nucleic acid are connected by a disulfide bond a composition for nucleic acid delivery comprising the hyaluronic acid-nucleic acid complex as an active ingredient a method for preparing the hyaluronic acid-nucleic acid complex and a method for in vivo delivery of nucleic acid, comprising administering the hyaluronic acid-nucleic acid complex to a subject are provided.
