Garcia - Martinez, Leon,Jensen, Anne Elisabeth Carvalho,Olson, Katie,Dutzar, Ben,Latham, John,Kovacevich, Brian,Smith, Jeffrey T.l.,Litton, Mark,Schatzman, Randall
申请号：
AU2009323009
公开号：
AU2009323009B2
申请日:
2009.11.24
申请国别(地区):
AU
年份:
2016
代理人:
摘要：
Disclosed are therapeutic methods using IL-6 antagonists such as an Ab 1 antibody or antibody fragment having binding specificity for IL-6 to prevent or treat disease or to improve survivability or quality of life of a patient in need thereof Patients will preferably comprise those exhibiting (or at πsk of developing) an elevated serum C-reactive protein level, reduced serum albumin level, elevated D-dimer or other coagulation cascade related proteιn(s), cachexia, fever, weakness and/or fatigue prior to treatment The subject therapies also may include the administration of other actives such as chemotherapeutics, anti-coagulants, statins, and others
