COMPOSITIONS AND METHODS FOR PRODUCTION OF COLD-CHAIN VACCINES

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专利权人:

University of Southern California

发明人:

Jae Jung,Daiki Hara,Byeong Chang,Francisca Gbormittah,Michael Reilly,Woo-Jin Shin

申请号：

US16669401

公开号：

US20200129610A1

申请日:

2019.10.30

申请国别(地区):

US

年份:

2020

代理人:

摘要：

This disclosure provides a novel lyophilized formulation that incorporates a surfactant solution to stabilize the Sabin inactivated polio vaccine and demonstrate the vaccine efficacy in an in vivo challenge model. Furthermore, SE-HPLC analysis of D-antigen content in in inactivated polio vaccine can be used to provide a method for high throughput evaluation of inactivated poliovirus stability.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/