PROBLEM TO BE SOLVED: To provide highly safe pharmaceuticals or foods and drink which suppress reduced muscle function or muscle atrophy and are useful for prevention of bedridden.SOLUTION: The invention relates to an atrogin-1 gene silencing agent containing ε-viniferin as an active ingredient.COPYRIGHT: (C)2015,JPO&INPIT【課題】筋機能低下や筋萎縮を抑制し、寝たきり予防に有用な、安全性が高い医薬品又は飲食品を提供する【解決手段】ε-ヴィニフェリンを有効成分とするアトロジン-1遺伝子発現抑制剤とする。【選択図】 図1