Christopher W. Widenhouse;Gary W. Knight;William B. Weisenburgh, II;John L. Stammen;Chester O. Baxter, III;Michael S. C;Charles J. Scheib;Frederick E. Shelton, IV;Mark H. Ransick;Chester O. Baxter; III;Stephanie A. Mutchler
发明人:
Chester O. Baxter, III,Frederick E. Shelton, IV,Charles J. Scheib,Christopher W. Widenhouse,William B. Weisenburgh, II,John L. Stammen,Mark H. Ransick,Stephanie A. Mutchler,Gary W. Knight,Michael S. C
申请号：
US13433141
公开号：
US20120241493A1
申请日:
2012.03.28
申请国别(地区):
US
年份:
2012
代理人:
摘要：
A tissue thickness compensator may generally comprise a first layer comprising a first biocompatible material sealingly enclosed in a water impermeable material and a second layer comprising a second biocompatible material comprising at least one encapsulation, wherein the first biocompatible material expands when contacted with a fluid. The tissue thickness compensator may comprise a haemostatic agent, an anti-inflammatory agent, an antibiotic agent, anti-microbial agent, an anti-adhesion agent, an anti-coagulant agent, a medicament, and/or pharmaceutically active agent. The encapsulation may comprise a biodegradable material to degrade in vivo and/or in situ. The tissue thickness compensator may comprise a hydrogel. The reaction product may comprise a fluid-swellable composition. Articles of manufacture comprising the tissue thickness compensator and methods of making and using the tissue thickness compensator are also described.
