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抗Aβ抗體製劑
专利权人:
JANSSEN ALZHEIMER IMMUNOTHERAPY;WYETH LLC
发明人:
LUISI, DONNA,WARNE, NICHOLAS, W.,KANTOR, ANGELA
申请号:
HK08110924.2
公开号:
HK1118723B
申请日:
2008.09.30
申请国别(地区):
HK
年份:
2013
代理人:
摘要:
The present invention provides formulations for maintaining the stability of A² binding polypeptides, for example, A² antibodies. Exemplary formulations include a tonicity agent such as mannitol and a buffering agent or amino acid such as histidine. Other exemplary formulations include an antioxidant in a sufficient amount as to inhibit by-product formation, for example, the formation of high molecular weight polypeptide aggregates, low molecular weight polypeptide degradation fragments, and mixtures thereof. The formulations of the invention optionally comprise a tonicity agent, such as mannitol, and a buffering agent or amino acid such as histidine. The formulations are suitable for several different routes of administration.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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