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Aminodihydrothiazine derivatives
专利权人:
Naotake Kobayashi
发明人:
Naotake Kobayashi,Kazuo Ueda,Naohiro Itoh,Shinji Suzuki,Gaku Sakaguchi,Akira Kato,Akira Yukimasa,Akihiro Hori,Yuji Koriyama,Hidekazu Haraguchi,Ken Yasui,Yasuhiko Kanda
申请号:
US13243971
公开号:
US08546380B2
申请日:
2011.09.23
申请国别(地区):
US
年份:
2013
代理人:
摘要:
A composition having BACE 1 inhibitory activity containing a compound represented by the formula (I):wherein ring A is an optionally substituted heterocyclic groupE is lower alkyleneX is SR1 is a hydrogen atom or lower alkylR2a, R2b, R3a, R3b, R4a and R4b is each independently a hydrogen atom, halogen, or hydroxy etc.n and m are each independently an integer of 0 to 3n+m is an integer of 0 to 3R5 is a hydrogen atom or substituted lower alkylor its pharmaceutically acceptable salt thereof.
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