antigen binding protein, methods of producing an antigen binding protein and identifying one or more antigen binding proteins, hybridoma, nucleic acid, cell, and genetically modified non-human animal.
ANDREW J. MURPHY,ASHIQUE RAFIQUE,ERGANG SHI,LYNN MACDONALD,ROBERT BABB,TAMMY T. HUANG
申请号:
BR112016021679
公开号:
BR112016021679A2
申请日:
2015.03.20
申请国别(地区):
BR
年份:
2018
代理人:
摘要:
Methods for making, identifying, isolating and/or making binding proteins that contain an immunoglobulin light chain variable domain, including a somatically hypermutated light chain variable domain, fused with a heavy chain constant region, are provided. Exemplary binding proteins specific to small molecules are also provided.