Ya-wei Qiang;Bart Barlogie;John D. Shaughnessy, Jr.;John D. Shaughnessy; Jr.
发明人:
John D. Shaughnessy, Jr.,Bart Barlogie,Ya-wei Qiang
申请号:
US12008771
公开号:
US08124087B2
申请日:
2008.01.14
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention is drawn to understanding lytic bone diseases. In this regard, the present invention discloses mechanism by which Wnt signaling antagonist inhibits bone differentiation. Also disclosed herein are methods to control bone loss, treat bone disease and prevent tumor growth in bones of individual.