ibuprofen pharmaceutical composition for ophthalmic use and tramadol. # The present invention relates to a pharmaceutical composition of tramadol and ibuprofen for ophthalmic use. It said composition is effective and safe for the treatment of inflammation and / or pain associated with ocular various diseases or conditions affecting the eye area. In particular, the ophthalmic composition of the invention is indicated, for example, for the treatment of pain and / or inflammation following ocular surgery.