A method of producing a flexible vessel model for simulating a surgical operation, which is a three-dimensional model being capable of reproducing an aneurysm or narrowing occurring in the artery or vein based on CT/MRI image data of a patient obtained in practice and thus allowing vascular therapy trainings and preoperative simulations, with the use of a precise lamination modeling machine, wherein a vascular model having an affected part is fabricated by using a lamination technique together with a supporting material for sustaining the shape of the three-dimensional model during the fabrication in the precise lamination modeling machine and, after the completion of the fabrication by the lamination machine technique, the supporting material is removed. Thus, it is possible to provide a three-dimensional vascular model whereby the shape of an aneurysm or narrowing occurring in the artery or vein, which is to be used in preoperative simulation of vascular therapy for the artery or vein, can be reproduced with the use of a flexible polymer model and thus vascular therapy trainings and preoperative simulation can be carried out by using the same.
