The present disclosure relates generally to the field of medical devices. In particular, the present disclosure relates to medical devices, systems, and methods for tightening, fastening, or anchoring in tissue. In one example, a system for tightening, fastening, or anchoring in tissue, may comprise a spring coil having a distal end, a stressed configuration, and an unstressed configuration; and a restraining tube having a lumen extending along a length of the tube. The spring coil may be removably receivable within the lumen to restrain the spring coil in the stressed configuration. Other embodiments are contemplated.