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Compounds act at multiple prostaglandin receptors giving a general anti-inflammatory response
专利权人:
发明人:
David F. Woodward,William R. Carling,Jose L. Martos,Jenny W. Wang,Jussi J. Kangasmetsa
申请号:
US14487412
公开号:
US09394284B2
申请日:
2014.09.16
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention provides a compound, that is a 1-[(2-{[(alkyl or aryl)methyl]oxy}halo or haloalkyl substituted-phenyl)alkyl]-5-hydrocarbyl or substituted hydrocarbyl-1H-pyrazole carboxylic acid or alkylenylcarboxylic acid or a hydrocarbyl or substituted hydrocarbyl sulfonamide of said carboxylic acid or said alkylenylcarboxylic acid, provided however said compound is not a 3-carboxylic acid, a sulfonamide thereof, or a 3-methylenylcarboxylic acid. The compound may be represented by the following formulaWherein R1, R2, R3, R4, R5, R6, X, W, X and Y are as defined in the specification. The compounds may be administered to treat DP1, FP, EP1, TP and/or EP4 receptor mediated diseases or conditions.
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