The present invention relates to the strain of Lactobacillus reuteri LMG P-27481 provided with anti-inflammatory activity, immunomodulatory activity and capability of inhibiting pathogenic microorganisms. The microorganism can result to be useful and contribute as probiotic in improving the man health status and preventing and/or treating gastrointestinal disturbances, with particular reference to the treatment of diarrhoea caused by Clostridium difficile. The invention also relates to pharmaceutical compositions or food or medical devices comprising the strain of Lactobacillus reuteri LMG P-27481.
