BIONICHE LIFE SCIENCES, INC;UNIVERSITY OF SASKATCHEWAN
发明人:
ANDREW A. PORTER,DAVID ASPER,DRAGAN ROGAN
申请号：
BRPI1014505
公开号：
BRPI1014505A2
申请日:
2010.04.06
申请国别(地区):
BR
年份:
2016
代理人:
摘要：
Compositions and methods for stimulating an immune response against Shiga toxin-producing Escherichia coli (STEC) antigens are disclosed. The compositions include a multiple epitope fusion protein comprising more than one epitope of an immunogenic STEC protein from more than one STEC serotype. Additional compositions include at least two purified STEC proteins, wherein the STEC proteins are selected from a full-length STEC protein, an immunogenic fragment or variant thereof, wherein at least one of the STEC proteins generates antibodies that react with STEC O157 and at least one other STEC serotype.
