A method for preventing and treating a headache in a patient is disclosed. The method includes locating one or more ligaments or muscle insertions that are associated with a cervical spine and a skull of the patient. The method further includes injecting into the determined one or more ligaments or muscle insertions an injectable regenerative solution that is derived from the patient to repair the one or more ligaments or muscle insertions. The method may further include determining a locus of the headache in the patient, determining one or more nerves associated with the locus of the headache, determining a set of the one or more ligaments or muscle insertions that are associated with the one or more nerves, and injecting the injectable regenerative solution into the determined set of the one or more ligaments or muscle insertions.