The invention refers to a method and an element (40) for biasing a cartridge (22) in a drug delivery device. The element (40) for biasing the cartridge (22) in a cartridge housing (6) of a drug delivery device and an according system comprising the element (40) and the drug delivery device are provided which is a self retained element (40) comprising a first member having a shape that allows passage of a spindle (60) of the drug delivery device. The self retained element (40) biases the cartridge (22) against an inner surface (28) of the cartridge housing (6). This cartridge (22) could be a removable cartridge. (Fig. 4)