EASTERN VIRGINIA MEDICAL SCHOOL;OLD DOMINION UNIVERSITY
发明人:
NUCCITELLI, RICHARD,BEEBE, STEPHEN J.,SCHOENBACH, KARL H.
申请号:
CA2643210
公开号:
CA2643210C
申请日:
2007.02.26
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
Methods for a new, drug-free therapy for treating solid skin tumors through the application of nanosecond pulsed electric fields ("nsPEFs") are provided. In one embodiment of the invention, the cells are melanoma cells, and the applied nsPEFs penetrate into the interior of tumor cells and cause tumor cell nuclei to rapidly shrink and tumor blood flow to stop. This new technique provides a highly localized targeting of tumor cells with only minor effects on overlying skin.