Frederic Rousseau;Joost Schymkowitz;Jie Xu;Frederik De Smet
发明人:
Joost Schymkowitz,Frederic Rousseau,Jie Xu,Frederik De Smet
申请号：
US14007602
公开号：
US09389219B2
申请日:
2012.03.26
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The disclosure relates to the fields of protein aggregation diseases including cancer. More specifically, it concerns a screening method for identifying compounds that inhibit or disrupt co-aggregation of one or more member proteins of a disease-related protein aggregome, in particular, a tumor-associated protein aggregome. Further, disclosed are agents and compounds identified by the screening method that can be applied to prevent or to treat protein aggregation diseases, such as cancer.
