The United States of America, as represented by The Secretary, Department of Health and Human Services;TdeltaS;The United States of America; as represented by The Secretary; Department of Health and Human Services
发明人:
Veech, Richard L.,Clarke, Kieran
申请号：
AU2013337308
公开号：
AU2013337308A1
申请日:
2013.11.05
申请国别(地区):
AU
年份:
2015
代理人:
摘要：
Described herein is the surprising discovery that ketone bodies protect cell and tissues from ionizing radiation. Based on this finding, methods of protecting animal tissue and cells from damage caused by radiation exposure are disclosed which include, contacting the tissue with a therapeutically effective amount of an agent including at least one ketone ester, thereby protecting the tissue from radiation damage. Ketone esters can be used to minimize, reduce and/or prevent tissue damage following intentional and accidental radiation exposure, as well as increasing the therapeutic efficacy of radiation therapies by protecting non-target tissue from incidental radiation damage.
