Jaenisch, Rudolf,Young, Richard A.,Marson, Alexander,Chevalier, Brett,Foreman, Ruth
申请号：
AU2008297011
公开号：
AU2008297011B2
申请日:
2008.08.29
申请国别(地区):
AU
年份:
2014
代理人:
摘要：
The invention provides compositions and methods of use in reprogramming somaticcells. Compositions and methods of the invention are of use, e.g., for generatingor modulating (e.g., enhancing) generation of induced pluripotent stem cellsby reprogramming somatic cells. The reprogrammed somatic cells are useful fora number of purposes, including treating or preventing a medical condition inan individual. The invention further provides methods for identifying an agentthat reprograms somatic cells to a pluripotent state and/or enhances the speedand/or efficiency of reprogramming. Certain of the compositions and methodsrelate to modulating the Wnt pathway.
