A method is provided for use with an ultrasound scanner, wherein an estimate value (particularly, a power level of the ultrasound scanner that is required to apply a desired acoustic pressure level to the body-part, the acoustic pressure level that is actually applied to the body-part when a specific power level is set, an acoustic attenuation that occurs within a patient between a transducer of the ultrasound scanner and the body-part and/or the acoustic attenuation that occurs within the patient between different body-parts) is determined according to a comparison between measurement data (based on a measurement response comprising a non-fundamental component of a measurement echo signal received in response to a measurement excitation signal) and corresponding reference data. Corresponding computer program product, system, therapeutic method, and diagnostic method are also provided.